The first thing that is different with the Note 6 is the existence of the USB Type-C connector, a first of its kind with Samsung flagships. You have the regular S-Pen, earphone jack port, and mono speakers placed below.
Galaxy Note 6 Renders – Source Onleaks and USwitch
Did you notice that the screen-to-body ratio and curved frame sides bear similar resemblance to the S7 Edge? Yes, it does, meanwhile, the back houses a slight camera bulge just like the way it is on the S7. I also noticed that you have a larger selfie camera sensor on the right and what could be an LED flashlight or an IRIS SCANNER (My bet is on the Iris Scanner, I think Samsung will stick with their illuminated selfies, just like the one on the S7). Lastly, you have the regular proximity sensors, volume buttons, and home button placements.
Galaxy Note 6 renders,
Dimension wise, the phone is a little bit more than the Note 5. Rumors have it that the Note 6 might come with a 6.04 x 2.90 x 0.31 inches (153.5mm x 73.9mm x 7.9mm) as opposed to the Note 5’s 6.03 x 3.00 x 0.30 inches (153.2 x 76.1 x 7.6 mm).
Whew! That is all I was able to get from the render. Notice anything else?